Below are a list of shortcuts that once you have used a few times you will find can save a lot of time.  You can download the shortcuts listed below at the following link: Google Drive.

Keyboard shortcuts

Shortcut Action
Alt Activate the menu bar in the active application (see also F10)
Alt+Enter Display the properties for the selected item
Alt+Esc Cycle through applications in the order in which they were opened
Alt+F1 Excel: Insert column chart.
Alt+F4 Close the active window. If there are no active windows, it opens up the Shutdown dialog (very useful if your mouse stops working and you need to restart)..
Alt+` Excel: View formulae in cells, not values
Alt+Page Up Move up one screen
Alt+Page Down Move down one screen
Alt+Left arrow Go back (see also Alt+Right arrow)
Alt+Right arrow Go forward (see also Alt+Left arrow)
Alt+Space Open the shortcut menu in the active application
Alt+Tab Switch between open apps
Alt++ Word: Insert an equation
Alt+X Word, Outlook, maybe others: Type a unicode code (a lot of these can be found on http://unicode.org/emoji/charts/full-emoji-list.html and http://www.fileformat.info/info/emoji/list.htm ) then press Alt-X to insert an emoticon (emoji) 🏖
Ctrl+1-9 Chrome: Change to the 1st, 2nd, 3rd, etc, open tab
Ctrl+A Select everything
Ctrl+B Make the selected text Bold
Ctrl+C Copy the selected text (see also Ctrl+Insert)
Ctrl+D Deletes the currently selected object (see also Delete)

Chrome: Add a bookmark

Edge: Add a favourite

Word: Open the font dialog

Ctrl+E Outlook: Search

Word: Toggle paragraph from Left to Centred.

Ctrl+F Open the Find/Search dialog (see also F3)

Outlook: Forward the currently selected email

Ctrl+G Word: Opens the Go To tab of the Find and Replace dialog.
Ctrl+H Chrome: opens your browser history in a new tab.

Word: Opens the Replace tab of the Find and Replace dialog.

Ctrl+I Make the selected text Italic
Ctrl+K Add a hyperlink to the selected text
Ctrl+N Open the New dialog

Chrome: Opens a new tab

Edge: Open a new window

Ctrl+O Open the Open dialog
Ctrl+P Open the Print dialog
Ctrl+R Browsers: Refresh/reload the page

Word: Align Right

Ctrl+U Underline the selected text
Ctrl+V Paste the selected text (see also Shift+Insert)
Ctrl+W Browsers: close the active tab
Ctrl+X Cut the selected text
Ctrl+Y Word: Repeat previous action
Ctrl+Z Undo previous action
Ctrl+Esc Open/close the Start menu
Ctrl++ Zoom in
Ctrl+- Zoom out
Ctrl+scroll mouse wheel Zoom in/out, depending on the direction you scroll
Ctrl+0 Return to the default zoom
Ctrl+Alt+Del Access the Security Options menu
Ctrl+Alt+V Word: Open Paste dialog
Ctrl+F4 Close the active document (in applications that are full-screen and allow you to have multiple documents open simultaneously)
Ctrl+Insert Copy the selected text (see also Ctrl+C)
Ctl+Shift+Esc Open the Task Manager
Ctrl+Shift+C Word: Copy on the formatting of the selected item.
Ctrl+Shift+V Word: Paste only the formatting.
Delete Deletes the currently selected object (see also Ctrl+D)
F1 Help
F2 Rename the selected item
F3 Chrome: Open the Find/Search dialog (see also Ctrl+F), then move from one matching search term to the next

Edge: Open the Find/Search dialog (see also Ctrl+F)

File Explorer: Open the Search ribbon

F4 Edge: Go to the address bar

File Explorer: Display the address bar list

F5 Refresh the active window
F6 Cycle through screen elements in a window
F9 Outlook: Send & receive
F10 Activate the menu bar in the active application (see also Alt)
Shift+Insert Paste the selected text (see also Ctrl+V)
Shift+F7 Word: Open the Thesaurus
Shift+F3 Word: Cycle the highlighted text from lower case to first letter capitalised to all capitalised
Shift+Tab Move to previous field (see also Tab)
Tab Move to next field (see also Shift+Tab)
Windows logo key Open/close the start menu (see also Ctrl+Esc)
Windows logo key+[1-9] Switch to the application in the [first to ninth] position on your task bar.
Windows logo key+Shift+[1-9] Open a new instance of the application in the [first to ninth] position on your task bar.
Windows logo key++ Open Windows Magnifier
Windows logo key+A Open the Action Centre
Windows logo key + B, wait then press Enter key Show hidden icons in the task bar
Windows logo key+C Open Cortana in listening mode
Windows logo key+D Show/hide the desktop
Windows logo key+E Open File Explorer
Windows logo key+F Open Feedback Hub
Windows logo key+H Share a screenshot of the open window via Mail, Facebook, Twitter, OneDrive etc, depending on the apps you have installed
Windows logo key+I Open Settings
Windows logo key+K Open Connect
Windows logo key+L Lock your PC or switch accounts
Windows logo key+M Minimise all open windows
Windows logo key+P Open Project, to manage your displays
Windows logo key+Q Open Cortana
Windows logo key+R Open Run dialog
Windows logo key+S Open Search
Windows logo key + Shift + S Capture a region of your screen and copy it to your clipboard (new in Windows 10 Creator’s Update)
Windows logo key+T Open the Desktop menu in the taskbar
Windows logo key+U Open the “Hear text and controls on the screen” settings
Windows logo key+Ctrl+F4 Close the virtual desktop you’re using (see also Windows logo key+Tab)
Windows logo key+Tab Add a virtual desktop (see also Windows logo key+Ctrl+F4)
Windows logo key+Ctrl+right arrow Switch between the virtual desktops you’ve created on the right